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灯心草化学成分的研究药学 |
[生化制药论文]
作者:田学军 李红霞 陈玉 王晓琼
【摘要】 目的对灯心草Juncus effusus L.石油醚和醋酸乙酯提取物的化学成分进行 研究 。 方法 运用正相和反相硅胶柱层析对灯心草石油醚和醋酸乙酯提取物进行分离纯化,并用波谱技术鉴定其结构。结果从灯心草石油醚提取物分得2个甾体化合物 stigmast4en6βol3one (1), (24R)stigmast4ene3one (2),从醋酸乙酯提取物分得两个二氢菲类化合物juncusol (3)和efffusol (4)。结论 化合物1和2均为首次从灯心草属植物中分得。
【关键词】 灯心草 灯心草属 甾体化合物
Abstract:ObjectiveTo investigate the chemical constituents of the stem of Juncus effusus L. Methods The constituents were isolated by normal-phase and reverse-phase silica gel column chromatography from the P.E. and EtOAc extract. Their structures were elucidated by spectral analysis. ResultsTwo steroid compounds were isolated from P.E. extract and identified as stigmast4en6βol3one (1), (24R)stigmast4ene3one (2), two 9,10dihydrophenanthrene compounds were isolated from EtOAc extract and identified as juncusol (3) and efffusol (4).ConclusionCompound 1 and 2 were isolated from Juncaceae plant for the first time.
Key words:Juncus effusus L.; Juncaceae; Steroids 灯心草Juncus effusus L.是灯心草科(Juncaceae)灯心草属(Juncus)多年生草本植物。通常生长在草甸、沼泽、水边及阴湿的环境中。在我国,灯心草是用于 治疗 失眠、发烧并具有清热利尿功效的传统药物[1]。国外学者的研究发现灯心草中的菲类化合物具有很……
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投稿人:7uy |
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最后编辑:fibg |
生化制药论文 | 生化制药论文 |
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