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中药天年饮对衰老大鼠免疫功能的影响药学 |
[生化制药论文]
【摘要】 目的探讨中药天年饮对衰老大鼠免疫功能的 影响 。 方法 40只SD大鼠随机分为4组,正常组、衰老模型组、天年饮用药组及阴性对照组,每组均为10只。D半乳糖连续腹腔注射制作亚急性衰老的大鼠模型。采用ELISA方法检测各组大鼠血清IL2及IL6的含量,MTT法检测脾淋巴细胞增殖转化,同时观察巨噬细胞的吞噬功能。结果天年饮可显著提高衰老大鼠血清IL2含量、脾淋巴细胞的增殖能力以及巨噬细胞的吞噬功能(用药组大鼠与衰老模型组大鼠比较,P<0.01,P<0.05);天年饮可明显降低衰老大鼠血清IL-6的含量(用药组大鼠与衰老模型组大鼠比较P<0.01)。 结论中药天年饮可增强衰老大鼠的免疫功能,具有一定延缓衰老的作用。
【关键词】 天年饮 免疫功能 大鼠
Influence of Traditional Chinese Medicine Tiannianyin on Immune Function of Aging Rats
Abstract:ObjectiveTo investigate the influence of traditional Chinese medicine Tiannianyin on immune function of aging rats. Methods40 SD rats were divided into 4 groups at random: normal group, aging model group, Tiannianyin group and negative control group, each group had 10 rats. The subacutely aging model rats were made by injecting D-gal into abdominal cavity continually. ELISA was used to detect the IL-2 and IL-6 contents in serum, MMT to detect the proliferation and transformation of spleen lymphocyte, and the macrophagic phagocytosis was also observed. ResultsTiannianyin not only significantly increased the IL-2 content, the proliferation and transformation of spleen lymphocyte and the macrophagic phagocytosis of aging rats (Tiannianyin group compared with aging group: P<0.01, P<0.05 ); but also obviousl……
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投稿人:7uy |
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最后编辑:fibg |
生化制药论文 | 生化制药论文 |
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