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肺表面活性物质治疗新生儿呼吸窘迫综合征临床疗效观察 |
[高血压医学论文]
【摘要】 目的:探讨肺表面活性物质对新生儿呼吸窘迫综合征(NRDS)的治疗效果。方法:将60例NRDS患儿随机分为治疗组29例和对照组31例,两组均给予nCPAP或机械通气等常规治疗,治疗组在此基础上给予气管内滴入肺表面活性物质,剂量为100 mg/kg。结果:治疗组和对照组存活率分别为96.55%、80.65%,治疗组存活率高于对照组,但差异无统计学意义(χ2=3.679,P>0.05);nCPAP或机械通气时间分别为(50.73±19.47)h、(77.34±19.69)h,治疗组通气时间缩短(t=9.13,P<0.05),机械通气所占比例分别为24.14%、54.84%,机械通气比例明显降低,两组比较差异有统计学意义(χ2=5.88,P<0.05);合并症的发生亦明显降低,除肺出血外差异均有统计学意义(P<0.05)。结论:肺表面活性物质对NRDS疗效满意,值得推广。
【关键词】 肺表面活性物质;新生儿;呼吸窘迫综合征
[Abstract]Objective:To explore the clinical effects of pulmonary surfactant on the treatment of neonatal respiratory distress syndrome (NRDS).Methods:60 cases NRDS were divided into two groups randomly with 29 cases in the treatment group and 31 cases in the control group.All cases were given routine treatments,such as nCPAP or mechanical ventilation.Besides the routine treatment,29 cases in the treatment group were given pulmonary surfactant with a dosage of 100 mg/kg.Results:Livability of the treatment group was 96.55% while that of the control group was 80.65%, having no statistical significance (χ2=3.679,P>0.05);nCPAP and mechanical ventilation periods were (5……
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高血压医学论文 | 高血压医学论文 |
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